The role of ursodeoxycholic acid in the treatment of hepatobiliary diseases in children

It is a well-known that significant part in the structure of digestive system diseases children compounds disorders biliary tract, which are based on violations regulation bile production and secretion. The topical issue search for safe effective drugs can prevent transformation into organic pathology, including cholecystitis, gallstone disease. One such ursodeoxycholic acid (UDCA), actively use pediatrics due to its hepatoprotective, immunomodulatory, choleretic, anticholestatic other properties. results literature review indicate UDCA therapy provides various clinical effects: it improves liver function by lowering level enzymes, prevents progression diseases. In addition, influence functional changes especially patients with hepatobiliary tract associate cholestasis, an alternative option treatment chronic Proven therapeutic efficacy, high quality safety create prospect this drug tract. No conflict interests was declared authors.